Main Category: Also in, the prevalence of certain forms of drug-resistant bacteria, called multidrug-resistant gram-negative (MDRGN) organisms, far surpassed the two other common antimicrobial-resistant infections in long term care, according to research conducted by researchers from the Institute of Jewish Studies SeniorLife for aging. Residents of long-term care facilities in one of the main reservoirs of antimicrobial resistant bacteria. Epidemiological studies have focused mainly on two common antimicrobial-resistant organisms - metitsillinorezistentnyh Staphylococcus aureas (
) and vancomycin-resistant enterococci (VRE). "It has become apparent that multidrug resistance among gram-negative bacteria is even more serious problem in these institutions, with nearly half of long-term care facility residents harboring multidrug-resistant gram-negative bacteria," write the researchers, the headed by Erin'O'Fallon IFAS, MD, MPH, in the January issue of the Journal of Gerontology: Medical Sciences. MDRGN infection can lead to toxins in the blood that cause inflammation and destroy healthy tissue. If untreated, these infections can be fatal. Over 80 percent of MDRGN in the study were resistant to commonly prescribed antimicrobial agents, including ciprofloxacin, trimethoprim-sulfamethoxazole and amipicillin / sulbactam. By definition, all identified bacteria MDRGN were stable, at least three different classes of antimicrobials, with one third of them resistant to four. These results, says Dr. O'Fallon, employees Geriatrist Hebrew Rehabilitation Center and Research Fellow in Medicine at Harvard Medical School, concern for therapeutic options available to physicians in the treatment of long-term care residents with MDRGN. Hospitals and long-term health care facilities only recently begun to include in their MDRGN surveillance of antimicrobial resistant bacteria and have extended requirements for contact precautions to MDRGN. Using a 1660 clinical cultures (urine, blood and wound specimens) obtained from residents of large urban long-term care facility, researchers found 180 cases MDRGN compared with 104 cases of MRSA and 11 cases of VRE. With further concern, they say, was a steady growth MDRGN for two-year study period, which increased from 7 percent in the first year to 13 percent last year. Doctor says O'Fallon infections caused MDRGN associated with higher mortality, prolonged hospitalization and increased costs compared with infections caused by gram-negative bacterial infections that can be effectively treated with. Risk factors for infection MDRGN in long-term care cheap strattera population include poor functional status, and promising antimicrobial activity. Note: Scientists of the Institute of HSL to research aging strict medical and social research, is a leader in developing strategies for maximizing individuals' strength, vigor and physical well-being and their cognitive and functional independence in late life. Hebrew SeniorLife Institute for Aging Research.
